Toads often have puffy looking pockets called paratoid glands located behind the ear that squirt poison at potential predators. So, if you've ever hear a dog "scream" after picking up an American Toad, now you know what happened!

Although frogs have poisonous skin glands, these toxins do not usually protect them from predatory mammals, birds, and snakes. Edible anurans have to rely on more than just poison glands which tend to work too late (i.e. after the predator has it in his mouth!)